Indentification of Breast Cancer Genes

Exome Sequencing Identifies Rare Deleterious Mutations in DNA Repair Genes FANCC and BLM as Potential Breast Cancer Susceptibility Alleles

ER Thompson, MA Doyle, GL Ryland, SM Rowley, DYH Choong, RW Tothill, H Thorne, DR Barnes, J Li, J Ellul, GK Philip, YC Antill, PA James, AH Trainer, G Mitchell, IG Campbell

2012-09-01

Despite intensive efforts using linkage and candidate gene approaches, the genetic etiology for the majority of families with a mu..

Analysis of RAD51C germline mutations in high-risk breast and ovarian cancer families and ovarian cancer patients

ER Thompson, SE Boyle, J Johnson, GL Ryland, S Sawyer, DYH Choong, null kConFab, G Chenevix-Trench, AH Trainer, GJ Lindeman, G Mitchell, PA James, IG Campbell

2012-01-01

There is strong evidence that overtly inactivating mutations in RAD51C predispose to hereditary breast and ovarian cancer but the ..